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Genes
⌊ Alleles
⌊ CDC Genes
⌊ Developmental Genes
⌊ Dominant Genes
⌊ Essential Genes
⌊ Gene Components
⌊ Immunoglobulin Genes
⌊ MDR Genes
⌊ Mitochondrial Genes
⌊ Multigene Family
⌊ Neoplasm Genes
⌊ Overlapping Genes
⌊ Pseudogenes
⌊ Recessive Genes
⌊ Regulator Genes
Genome Components
⌊ Intergenic DNA
⌊ Genetic Loci (Genetic Locus)
⌊ Unstable DNA Sequence
⌊ Microbiological Attachment Sites
⌊ Operons
 
 
See Also ↔
 
 

Genes

 
“Genes”  

Gene

    In our body's cells, our Genes are part of a complex interactive biological system, that codes for specific proteins and expresses those proteins in response to any signals received from biological events.

Locus

    In our body's cells, Genes are specific sequences of nucleotides along a molecule of DNA (DeoxyriboNucleic Acid) which represent our functional units of Heredity.

In our body's cells, Genes are the specific segments of DeoxyriboNucleic Acid (DNA) found on chromosomes.

In our body's cells, each gene has a designated place on every chromosome, called a locus.
    Examples of subsets, concepts, subjects, topics and other related entities of genes and associated proteins include:

*
[90500]
“SRY Gene”  
Chromosome Y bw

SRY

    In our body's cells, the SRY gene, aka sex determining region Y (testis-determining factor), is one of our human genes, belonging to the SRY-box transcription factors genes.

SRY Gene

    In our body's cells, the chromosomal locus of the SRY gene is found on chromosome Y at the Yp11.2 position.
[56300]
“Histocompatibility Complex (MHC) ”  

Major Histocompatibility Complex (HLA Complex)

    In our body, Major Histocompatibility Complex (MHC), aka Histocompatibility Complex (HLA Complex), is a genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) Transplantation Antigens.
    In our body's cells, the major Histocompatibility Complex (HLA Complex) is a large genomic region or gene family that encodes MHC molecules. The MHC protein molecules act as "signposts" to alert the immune system if a foreign material is present inside a cell.
    The major histocompatibility complex gene family (HLA gene family) contains the following genes within two subclasses:
  • MHC class I genes (major histocompatibility complex class I genes), aka histocompatibility complex class I gene family (HLA class I gene family)
    • HLA-A gene (major histocompatibility complex, class I, A)
    • HLA-B gene (major histocompatibility complex, class I, B)
    • HLA-C gene (major histocompatibility complex, class I, C)
    • HLA-E gene (major histocompatibility complex, class I, E)
    • HLA-F gene (major histocompatibility complex, class I, F)
    • HLA-G gene (major histocompatibility complex, class I, G)
    • HLA-H gene (major histocompatibility complex, class I, H pseudogene)
    • HLA-J gene (major histocompatibility complex, class I, J pseudogene)
    • HLA-K gene (major histocompatibility complex, class I, K pseudogene)
    • HLA-L gene (major histocompatibility complex, class I, L pseudogene)
    • HLA-N gene (major histocompatibility complex, class I, N pseudogene)
    • HLA-P gene (major histocompatibility complex, class I, P pseudogene)
    • HLA-S gene (major histocompatibility complex, class I, S pseudogene)
    • HLA-T gene (major histocompatibility complex, class I, T pseudogene)
    • HLA-U gene (major histocompatibility complex, class I, U pseudogene)
    • HLA-V gene (major histocompatibility complex, class I, V pseudogene)
    • HLA-W gene (major histocompatibility complex, class I, W pseudogene)
    • HLA-X gene (major histocompatibility complex, class I, X pseudogene)
    • HLA-Y gene (major histocompatibility complex, class I, Y pseudogene)
    • HLA-Z gene (major histocompatibility complex, class I, Z pseudogene)
  • MHC class I genes (major histocompatibility complex class I genes), aka histocompatibility complex class I gene family (HLA class I gene family)
    • HLA-DMA gene (major histocompatibility complex, class II, DM alpha)
    • HLA-DMB gene (major histocompatibility complex, class II, DM beta)
    • HLA-DOA gene (major histocompatibility complex, class II, DO alpha)
    • HLA-DOB gene (major histocompatibility complex, class II, DO beta)
    • HLA-DPA1 gene (major histocompatibility complex, class II, DP alpha 1)
    • HLA-DPA2 gene (major histocompatibility complex, class II, DP alpha 2 pseudogene)
    • HLA-DPA3 gene (major histocompatibility complex, class II, DP alpha 3 pseudogene)
    • HLA-DPB1 gene (major histocompatibility complex, class II, DP beta 1)
    • HLA-DPB2 gene (major histocompatibility complex, class II, DP beta 2 pseudogene)
    • HLA-DQA1 gene (major histocompatibility complex, class II, DQ alpha 1)
    • HLA-DQA2 gene (major histocompatibility complex, class II, DQ alpha 2)
    • HLA-DQB1 gene (major histocompatibility complex, class II, DQ beta 1)
    • HLA-DQB2 gene (major histocompatibility complex, class II, DQ beta 2)
    • HLA-DQB3 gene (major histocompatibility complex, class II, DQ beta 3)
    • HLA-DRA gene (major histocompatibility complex, class II, DR alpha)
    • HLA-DRB1 gene (major histocompatibility complex, class II, DR beta 1)
    • HLA-DRB2 gene (major histocompatibility complex, class II, DR beta 2 pseudogene)
    • HLA-DRB3 gene (major histocompatibility complex, class II, DR beta 3)
    • HLA-DRB4 gene (major histocompatibility complex, class II, DR beta 4)
    • HLA-DRB5 gene (major histocompatibility complex, class II, DR beta 5)
    • HLA-DRB6 gene (major histocompatibility complex, class II, DR beta 6 pseudogene)
    • HLA-DRB7 gene (major histocompatibility complex, class II, DR beta 7 pseudogene)
    • HLA-DRB8 gene (major histocompatibility complex, class II, DR beta 8 pseudogene)
    • HLA-DRB9 gene (major histocompatibility complex, class II, DR beta 9 pseudogene)
[72388]
“Heredity”  
Heredity … … …
[91581]

References:

Fuqua JS.   et al "Analysis of the SRY gene in gonadal tissue of subjects with 46,XY gonadal dysgenesis"   J Clin Endocrinol Metab. 1997 Feb;82(2):701-2
  Xia XY.   et al "A duplication upstream of SOX9 was not positively correlated with the SRY‑negative 46,XX testicular disorder of sex development: A case report and literature review"   Mol Med Rep. 2015 Oct;12(4):5659-64  
  Sekido R.   et al "Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer"   Nature. 2008 Jun 12;453(7197):930-4  
Kennerknecht I.   et al "Agonadism in two sisters with XY gonosomal constitution, mental retardation, short stature, severely retarded bone age, and multiple extragenital malformations: a new autosomal recessive syndrome"   Am J Med Genet. 1995 Oct 23;59(1):62-7
Servenius B.   et al "Molecular map of the human HLA-SB (HLA-DP) region and sequence of an SB alpha (DP alpha) pseudogene"   EMBO J. 1984 Dec 20;3(13):3209-14
  Shiina T.   et al "Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region"   Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13282-7  
   †The statements on this Web site have not been evaluated by the Food and Drug Administration (FDA). And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. Nothing presented here is intended as a substitute for prescription medication or any other medical treatment prescribed by your doctor.
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