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Histamine Receptors
⌊ Histamine H1 Receptors
⌊ Histamine H2 Receptors
⌊ Histamine H3 Receptors
⌊ Histamine H4 Receptors (H4 Receptors)
Biogenic Amine Receptors
⌊ Serotonin Receptors (Tryptamine Receptors)
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See Also ↔
 
 

Histamine Receptors

 
“Histamine Receptors”  
    In our body, the biogenic amine receptors, Histamine Receptors are cell surface proteins that bind the specific biogenic amine (histamine) with a high affinity which then trigger intracellular changes influencing the behavior of cells. *
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“Histamine Receptors H1 (H1 Receptors)”  

Histamine H1 Receptors

    In our body, Histamine H1 Receptors (H1 Receptors), as g-protein-coupled receptors, are a class of histamine receptors discriminated by their pharmacology and mode of action, mostly operating through the inositol phosphate/diacylglycerol second messenger system, associated with the HRH1 gene.
    In our body, among the many responses mediated by Histamine H1 Receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis.
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“Histamine Receptors H2 (H2 Receptors)”  

Histamine H2 Receptors

    In our body, Histamine H2 Receptors, as g-protein-coupled receptors, are a class of histamine receptors discriminated by their pharmacology and mode of action, associated with the HRH2 gene.
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“Histamine Receptors H3 (H3 Receptors)”  

Histamine H3 Receptors

    In our body, Histamine H3 Receptors are a class of histamine receptors discriminated by their pharmacology and mode of action, first recognized as inhibitory autoreceptors on histamine-containing nerve terminals and in the regulating the release of several neurotransmitters in both the central and peripheral nervous systems associated with the HRH3 gene.
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“Histamine H4 Receptors (H4 Receptors)”  

Histamine Receptors H4 (H4 Receptors)

    In our body, Histamine H4 Receptors (H4 Receptors) are a class of histamine receptors discriminated by their pharmacology and mode of action, associated with the HRH4 gene.
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References:

  Panula P.   et al "International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors"   Pharmacol Rev. 2015 Jul;67(3):601-55  
Fukui H.   et al "Molecular cloning of the human histamine H1 receptor gene"   Biochem Biophys Res Commun. 1994 Jun 15;201(2):894-901
Lovenberg TW.   et al "Cloning and functional expression of the human histamine H3 receptor"   Mol Pharmacol. 1999 Jun;55(6):1101-7
Nakamura T.   et al "Molecular cloning and characterization of a new human histamine receptor, HH4R"   Biochem Biophys Res Commun. 2000 Dec 20;279(2):615-20
Oda T.   et al "Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes"   J Biol Chem. 2000 Nov 24;275(47):36781-6
   †The statements on this Web site have not been evaluated by the Food and Drug Administration (FDA). And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. Nothing presented here is intended as a substitute for prescription medication or any other medical treatment prescribed by your doctor.
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