April 03, 2010 - Saporo, Japan - Grapefruit juice improved intestinal absorption of coenzyme Q10 (CoQ10) by about 50 per cent, says Japanese researchers in a 2010 study.
The juice inhibits a protein in the membrane of cells called P-glycoprotein (P-gp), which thereby leads to an increased absorption of CoQ10, according to results of a laboratory study published in Food Chemistry.
“We have demonstrated that a higher cellular uptake of CoQ10 was achieved in the presence of grapefruit juice,” wrote the Japanese researchers, led by Ken Iseki from Hokkaido University.
Coenzyme Q10 (ubiquinone, CoQ10) is a fat-soluble vitamin-like substance present in every cell of the body and it serves as a coenzyme for several of the key enzymatic steps in the production of energy inside the cell. In healthy individuals normal CoQ10 levels are maintained both by CoQ10 intake and by the body's synthesis of CoQ10. CoenzymeQ10 has no known toxicity or side effects.
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